• MEMBDEATH: Towards A Novel Therapeutic Approach
2024
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    Experimental and computational approaches for membrane protein insertion and topology determination.

    Reference

    Duart G, Graña-Montes R, Pastor-Cantizano N, Mingarro I. Experimental and computational approaches for membrane protein insertion and topology determination. Methods. 2024 Apr 9;226:102-119. doi: 10.1016/j.ymeth.2024.03.012. Epub ahead of print. PMID: 38604415.

    [DOI] [Abstract] [Full text] [Full text PDF]

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    Cetylpyridinium chloride and chlorhexidine show antiviral activity against Influenza A virus and Respiratory Syncytial virus in vitro.

    Reference

    Rius-Salvador M, García-Múrria MJ, Rusu L, Bañó-Polo M, León R, Geller R, Mingarro I, Martinez-Gil L. Cetylpyridinium chloride and chlorhexidine show antiviral activity against Influenza A virus and Respiratory Syncytial virus in vitro. PLoS One. 2024 Feb 16;19(2):e0297291. doi: 10.1371/journal.pone.0297291. PMID: 38363760; PMCID: PMC10871507.

    [DOI] [Abstract] [Full text] [Full text PDF]

2023
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    Identification of small molecules capable of enhancing viral membrane fusion.

    Reference

    García-Murria MJ, Gadea-Salom L, Moreno S, Rius-Salvador M, Zaragoza O, Brun A, Mingarro I, Martínez-Gil L. Identification of small molecules capable of enhancing viral membrane fusion. Virol J. 2023 May 24;20(1):99. doi: 10.1186/s12985-023-02068-1. PMID: 37226231; PMCID: PMC10206591.

    [DOI] [Abstract] [Full text] [Full text PDF]

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    Computational design of BclxL inhibitors that target transmembrane domain interactions.

    SEBBM article of the month

    Reference

    Duart G, Elazar A, Weinstein JY, Gadea-Salom L, Ortiz-Mateu J, Fleishman SJ, Mingarro I, Martinez-Gil L. Computational design of BclxL inhibitors that target transmembrane domain interactions. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2219648120. PMID: 36881618.

    [DOI] [Abstract] [Abstract] [Index] [Full text] [Full text PDF]

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    Proteotranscriptomic analysis of advanced colorectal cancer patient derived organoids for drug sensitivity prediction.

    Reference

    Papaccio, F., García-Mico, B., Gimeno-Valiente, F. et al. Proteotranscriptomic analysis of advanced colorectal cancer patient derived organoids for drug sensitivity prediction. J Exp Clin Cancer Res 42, 8 (2023)

    [DOI] [Full text] [Full text PDF] [Full text ePub]